Published in Gene Therapy Weekly, May 30th, 2002
The inherited disease is marked by immune system deficiency and the formation of lesions called granulomas that can form throughout the body and beneath the skin.
By using a genetically engineered murine model of X-linked chronic granulomatous disease (X-CGD), investigators have designed a cutaneous model of the disease by injecting the genetically manipulated mice with hyphae from the fungus Aspergillus fumigatus.
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