Insulin Therapy

Plasmid injection in non-neuroendocrine cells stimulates insulin secretion

Published in Gene Therapy Weekly, May 30th, 2002

by Sonia Nichols, senior medical writer - Building upon the latest of gene transfer techniques, researchers in England have found a way to get non-neuroendocrine cells to produce bioactive human proinsulin in a series of studies of cells grown in culture and in animal models.

Using gene therapy to stimulate nonhormonal cells to produce insulin might be of some use for treating type 1 diabetics, whose pancreatic cells do not produce enough insulin to metabolize glucose. Although former trials of pancreatic cell transplantation have involved the use of strong immunosuppressive agents, more modern ones are investigating the transplant of such cells without the need for...

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Source: Gene Therapy Weekly (2002-05-30)

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