Published in Gene Therapy Weekly, June 20th, 2002
The technology, invented by Dr. Richard T. Pon of the University of Calgary, was licensed through University Technologies International, Inc., of Calgary, Alberta, Canada (UTI).
Current oligo synthesis starts with a solid support, a foundation on which to build the oligo, preloaded with a linker and the first nucleic acid base. The linker couples the first base to the foundation and can be cleaved, or cut, at the end of the building process to remove the foundation from the finished oligo. Other...
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