Transduction

Gene transfer to cancers residing in muscles may present problem

Published in Gene Therapy Weekly, July 11th, 2002

by Sonia Nichols, senior medical writer - Scientists who are currently devising strategies for treating recurrent cancer cells with gene therapy may run into problems when the cells are located in muscle tissues.

Researchers may need to take a different approach to the delivery of these therapies, according to a study undertaken by a team in London, U.K.

One of the study's investigators, Roth Oakley of King's College Hospital, noted that while preclinical studies of rescue gene therapy have shown benefits in immunodeficient animal models with subcutaneous tumors, in reality radioresistant tumors that may recur after surgery can arise deep within the...

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Source: Gene Therapy Weekly (2002-07-11)

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