Pulmonary Diseases

Copernicus announces breakthrough in nonviral gene transfer to the lung

Published in Gene Therapy Weekly, July 18th, 2002

Copernicus Therapeutics, Inc., presented data at the American Society of Gene Therapy meeting showing that their compacted DNA formulation can effectively transfect murine lung, establishing a robust DNA drug delivery platform for pulmonary and systemic diseases.

Mark J. Cooper, MD, senior vice president of science and medical Affairs said, "Our compacted DNA nanoparticles have been optimized to effectively deliver genes to pulmonary epithelial cells. Our pharmaceutical preparation of compacted DNA is extremely stable in serum and other biological fluids, and has an extended shelf-life at either 4(degree)C or room temperature. The small size of our DNA particles...

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Source: Gene Therapy Weekly (2002-07-18)

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