Cancer Therapy

Scientists design gene-tipped tumor regressor 'smartbombs'

Published in Gene Therapy Weekly, August 1st, 2002

A group of researchers from the Scripps Research Institute (TSRI) have demonstrated what, in principle, could be a new way of treating cancer and several other diseases where angiogenesis occurs. Angiogenesis is a crucial process in cancer, and, when blocked, improves a patient's prognosis.

In cancer-related angiogenesis, tumors develop their own blood supplies by causing cells that line blood vessels to proliferate, forming new vessels and bringing more blood to the tumor. The increased oxygen and nutrients the tumors receive allow them to grow and enable certain metastatic cells to leave the tumor, enter the bloodstream, migrate to other tissues of the body, and...

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Source: Gene Therapy Weekly (2002-08-01)

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