Published in Gene Therapy Weekly, September 12th, 2002
Though gene therapy has the potential for treating traumatic brain injury (TBI), virus-based delivery vehicles typically ignite inflammatory response mechanisms and in some instances can be cytotoxic, hampering gene therapy effectiveness, according to Linglong Zou and colleagues, Baylor College of Medicine, Houston, Texas.
Zou and coauthors have developed a less immunogenic gene delivery system composed of an adenoviral construct missing...
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