Published in Gene Therapy Weekly, September 26th, 2002
Although ODNs are considered valuable molecules for use in gene therapies, their properties often make them less than optimal barrier crossers. Enlisting a more effective carrier vehicle would be one way to overcome that problem, scientists say.
"This carrier should assist antisense ODNs to penetrate the cell membrane and, once inside the cell, release the ODNs and make them available for target binding," Qiang...
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