Antiangiogenic Gene Therapy
Kallistatin is a new inhibitor of tumor neovascularization and growth
Published in Gene Therapy Weekly, January 9th, 2003
"Kallistatin is a unique serine proteinase inhibitor (serpin) and a heparin-binding protein. It has been localized in vascular smooth muscle cells and endothelial cells of human blood vessels, suggesting that kallistatin may be involved in the regulation of vascular function," wrote R.Q. Miao and colleagues, who previously demonstrated "that kallistatin plays a role in neointima hyperplasia."
In their current study, published in the journal Blood, Miao's group "investigated the potential role of kallistatin in...
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Source: Gene Therapy Weekly (2003-01-09)
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