Published in Gene Therapy Weekly, January 16th, 2003
However, ribozymes, RNA with enzymatic properties, tend to be unstable. Scientists in Germany may have found a feasible way to override that instability.
The scientists work at Phllips-University Marburg in Marburg, Germany, where they have generated ribozymes that are complexed with low-molecular-weight polyethyleneimine (LMW-PEI). According to researchers, the ribozyme/LMW-PEI constructs have an unparalleled ability to target protein construction with stability and specificity.
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