Susan Hasty, Publisher
Table of Contents . . . January 23rd, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Kidney Transplantation - Limitations of gene transfer for controlling graft injury unresolved
Restenosis - Chimeric ribozyme prevents hyperplasia in treated arteries
Bioengineering - Insulin release system gets boost from preproinsulin gene
Dystrophic Epidermolysis Bullosa - Researchers use gene therapy to prompt mouse cells to produce human collagen
Myotonia Congenita - Novel gene therapy approach shows promise at VUMC
Thyroid Cancer - Rodent gene better than human ones for concentrating radioisotope
Transduction - Modified retrovirus able to guide macrophages after gene transfer
Animal Models - Systemic administration of AS-ODNs used to create Apo E-deficient mice
Arteriosclerosis - Combination of therapies improves blood flow to impaired hearts
Arthritis - Dendritic cells engineered to express FasL inhibit disease progression mice
Breast Cancer - M-CSF, IL-2 coexpression can augment the effect of HSVtk suicide gene therapy
Cancer Gene Therapy - Data reported from phase I trial of ISIS 104838
Cancer Gene Therapy - Id2 gene is novel target of EWS-ETS fusion proteins
Cancer Gene Therapy - Mechanism of fusogenic membrane glycoprotein-mediated cell killing described
Cancer Therapy - INGN 241 shows antitumor activity
Cardiomyopathy - Defects in molecular trigger for muscle growth are important genetic cause
Colitis - AS-ODNs to nuclear enzyme ameliorate disease in IL-10-deficient mice
Colon Cancer - Cell growth suppressed in nude mice by targeting beta-catenin/TCF pathway
DNA Vaccines - B virus glycoprotein antibodies induced by DNA immunization characterized
DNA Vaccines - Salivary gland delivery of pDNA-cationic lipoplexes is immunogenic
DNA Vaccines - Study compares oral vs. intramuscular immunization
Diabetes Vaccine - Neurologic disorders not associated with MMR vaccination
Gene Delivery - AS-ODNs transferred to HCECs in vitro via ultrasound and microbubbles
Gene Delivery - Mimicked gene defect affords HIV protection
Gene Delivery - Systemic gene therapy by liposomal delivery of E1A gene shows promise
Gene Transfer - Transcutaneous ultrasound augments naked DNA transfection of skeletal muscle
Gene Transfer - Ultrasound boosts gene expression in dystrophic muscles
Influenza - Recombinant adenovirus encodes swine H3N2 influenza virus HA gene
Pediatric Vaccine - Robust immune response to DNA vaccine found in infants
Squamous Cell Carcinoma - Combined endostatin and EGF receptor-antisense therapy may hold promise
Stem Cell Research - Cytokines improve LV transduction of repopulating hematopoietic cells
Stem Cell Transduction - Improved protocol maximizes CD34+ cell transduction from cord blood
Tumors - MDA-7 activates immune system, has antiangiogenic properties
Vector Development - An angiogenic, endothelial cell-targeted, polymeric gene carrier described
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