Virology
Adenoviruses ideal for assessing angiogenic genes in assays
Published in Gene Therapy Weekly, March 6th, 2003
"The chicken chorioallantoic membrane CAM assay represents one of the most widely used in vivo screening assays for genes with angiogenic (blood vessel-inducing) or angiostatic (inhibition of vessel formation or their destruction) activities," stated K. Schughart and coauthors, GBF, German Research Center for Biotechnology.
"Here, we show that adenovirus gene transfer vectors infect cells in the CAM and lead to expression of the viral transgene. Furthermore, infection with an adenovirus vector...
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Source: Gene Therapy Weekly (2003-03-06)
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