Gene Transfer
Porous scaffolds facilitate delivery of nonviral DNA
Published in Gene Therapy Weekly, March 13th, 2003
According to recent research from the United States, "the inductive approach to tissue engineering combines three-dimensional porous scaffolds with drug delivery to direct the action of progenitor cells into a functional tissue. We present an approach to fabricate scaffolds capable of controlled, sustained delivery by the assembly and subsequent fusion of drug-loaded microspheres using a gas foaming/particulate leaching process."
"DNA-loaded microspheres were fabricated from the copolymers of lactide and glycolide (PLG) using a cryogenic double emulsion process," explained J.H. Jang and...
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Source: Gene Therapy Weekly (2003-03-13)
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