Type 1 Diabetes

Genetically modified liver cells can store, process, and secrete insulin

Published in Gene Therapy Weekly, March 27th, 2003

by Sonia Nichols, senior medical writer - Genetically modified neoplastic liver cells can be made to generate and secrete insulin in response to glucose, according to medical researchers in Australia.

They have made HUH7 liver cancer cells produce and secrete insulin in mice. Genetically altered cells like those created by the researchers might be valuable for treating humans who are diagnosed with type 1 diabetes, an illness marked by inadequate insulin production.

For their study, B.E. Tuch and colleagues at the University of South Wales transfected HUH7 cells with human insulin cDNA. The gene was turned on with help from the cytomegalovirus...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (2003-03-27)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry