Biotechnology
Silencing RNAs are new tools for elucidating mammalian cell gene function
Published in Gene Therapy Weekly, April 10th, 2003
"RNA interference (RNAi) is a RNA-mediated sequence-specific gene silencing mechanism. Recently, this mechanism has been used to down-regulate protein expression in mammalian cells by applying synthetic- or vector-generated small interfering RNAs (siRNAs). However, for the evaluation of this new knockdown technology, it is crucial to demonstrate biological consequences beyond protein level reduction," researchers in Germany report.
"Here, we demonstrate that this new siRNA-based technology is suitable to analyze protein functions using the phosphatidylinositol (PI) 3-kinase...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2003-04-10)
More Articles from Gene Therapy Weekly
- Cancer Therapy
Interleukin-12 gene therapy is a viable alternative for treating thyroid cancer - Type 1 Diabetes
Gene therapy prevents diabetic recurrence after islet cell transplantation - Colon Cancer
Cisplatin resistance could be defeated with gene targeting - Liver Therapy
A new technique uses gene transfer to improve liver cell transplantation - Ophthalmology
Ocular injection of pseudotyped adenoviral vectors could prevent blindness - Respiratory Disease
Sodium caprate enhances DEAE dextran-mediated gene delivery to the lungs - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
