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Coronary Artery Disease

Gene therapy study under way

Published in Gene Therapy Weekly, April 24th, 2003

A 56-year-old East Brunswick, New Jersey, man has become the first patient to enter a Robert Wood Johnson University Hospital research study of a gene therapy product, called Ad5FGF-4, designed to stimulate the body's natural ability to grow new blood vessels.

Dr. Abel Moreyra, MD, director of the Heart Center of New Jersey, administered a one-time, intracoronary injection by heart catheterization, giving the patient either Ad5FGF-4 or a placebo. In this double-blind study, neither Moreyra nor the patient knew whether the injection contained the investigational gene therapy product or the placebo.

After receiving the injection, the patient will be...

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