Cardiovascular Disease
Ultrasound-targeted antisense oligonucleotide attenuates cytokine production
Published in Gene Therapy Weekly, April 24th, 2003
According to recent research from the United States, "ultrasound contrast agents are now emerging as effective vehicles for delivering therapeutic agents to target tissues. In the present study, we used ultrasound-targeted, contrast-bound antisense oligonucleotides to inhibit the expression of tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine with negative inotropic effects."
"We compared the efficacy of left ventricular vs. intravenous administration and determined the optimal time for delivery. WKY rats were treated with perfluorocarbon-exposed...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2003-04-24)
More Articles from Gene Therapy Weekly
- Antiangiogenesis
Tissue inhibitor of metalloproteinase-3 limits angiogenesis and neuroblastoma - Rheumatoid Arthritis
Antioxidant enzyme gene therapy relieves joint inflammation in arthritic models - Cancer Gene Therapy
Timing is crucial for HSV-1 thymidine kinase/ganciclovir-mediated cytotoxicity - Glioma
Melanoma differentiation associated gene-7 reduces brain cancer tumorigenicity - Sly Syndrome
Early gene therapy mitigates the manifestations of mucopolysaccharidosis VII - Autoimmune Disease
Genetically modified bone marrow could reverse some autoimmune disorders - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
