Published in Gene Therapy Weekly, May 1st, 2003
Writing in the journal Gene Therapy, H. Gollins and colleagues at the University of London's Imperial College of Science, Technology, & Medicine, said, "The efficiency of plasmid gene transfer in skeletal muscle is significantly enhanced by pretreatment with hyaluronidase and the application of an electrical field to the muscle following the injection of plasmid DNA, a process referred to as electrotransfer. However, the presence of increased levels of connective tissue in muscular dystrophies, such as...
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