Bioengineering
AMEGA facilitates the selection of genetically modified cell populations
Published in Gene Therapy Weekly, June 5th, 2003
"While antibiotic selection has been routinely used for the selection of genetically modified cells, administration of cytotoxic drugs often leads to deleterious effects not only to inert cells but also to transfected or transduced ones," researchers in Japan report.
"In this study, we propose an antigen-mediated genetically modified cell amplification (AMEGA) system employing antibody/receptor chimeras without antibiotic selection," wrote M. Kawahara and colleagues, University of Tokyo, Graduate School Engineering.
"Based on a rational design where the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2003-06-05)
More Articles from Gene Therapy Weekly
- Liver Cirrhosis
Interferon-alpha gene transfer improves liver cirrhosis in rodent models - Selective Transfection
ONYX-015 is deemed safe for patients with recurrent cancer - Hepatocellular Carcinoma
Enhanced specific gene expression is a new strategy for treating liver cancer - Parkinson Disease
Insulin-like growth factor-1 protects human dopaminergic cells from toxin - Virology
Advanced generation lentiviruses are good for transducing cardiomyocytes - Apoptosis
Tiny protein prevents disease-related cell death - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
