Susan Hasty, Publisher
Table of Contents . . . June 19th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Hepatitis C Virus - Suicidal gene therapy
Renal Disease - Gene instillation prevents renal injury caused by protein overload
Neurology - The vitreous humor offers a new route for central nervous system gene delivery
Pulmonary Medicine - Cyclic stretch augments gene transfer in alveolar epithelial cells
Pulmonary Medicine - Epstein-Barr vector prolongs gene expression in mouse lung endothelial cells
Vector Development - Rapid onset diseases could be treated with vectors offering quick transfection
Arteriogenesis - Arterioles form next to VEGF-induced angiogenesis in treated muscle tissues
Bioengineering - Eurkaryotes secrete functionally active immunotoxins under the right conditions
Canavan Disease - Gene therapy pioneered at UNC is given to children with rare disorder
Cancer Immunotherapy - Cytokine gene therapy combinations could become viable anticancer agents
Cancer Vaccine - Allovectin-7 shows promise against metastatic melanoma
Cognition - Antisense to NMDA-NR1 limits prepulse inhibition but not spatial memory
Gene Delivery - Annealed complexes make oligonucleotides more appealing to mitochondria
Gene Silencing - Vector-based RNA interference knocks down genes associated with angiogenesis
Gene Targeting - Noninvasive imaging monitors PEI/DNA targeted specificity in tumors
Gene Transfer - Recombinant single-chain antibodies with oligopeptide tails steer gene delivery
Hepatology - Gene-encoded adeno-associated virus knocks down glycogen storage disease
High Cholesterol - Gene therapy lowers cholesterol in a model of familial hypercholesterolemia
Immunology - Gene transduction corrects T cells in patients with Wiskott-Aldrich syndrome
Ischemic Stroke - Neurotrophic factor prevents delayed neuronal death after transient ischemia
Melanoma - Study offers hope for first new treatment in decades
Muscular Dystrophy - U7 small nuclear RNAs use exon skipping to induce dystrophin gene correction
Oncology - Diphtheria toxin A-chain expression inhibits bladder cancer cell growth
Patents - New manufacturing patent issued for AIDS vaccine, cystic fibrosis and arthritis programs
Pulmonary Hypertension - VEGF-B overexpression attenuates chronic hypoxic hypertension in the lungs
Retroviral Vectors - Lability depends on host cell and cholesterol levels of viral lipid shell
Therapy - Genteric to collaborate to deliver DNA into the salivary gland
Type 2 Diabetes - GLP-1 gene transfer improves insulin secretion in rodent diabetes models
Vector Development - Protein expression enhanced in E. coli by pET-DB vector
Vectors - Study highlights potential danger of gene therapy
Virology - Replicating adenovirus codes for multiple genes using native promoters
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