Immunology
Cross-reactivity of adenovirus-specific T cells has therapeutic implications
Published in Gene Therapy Weekly, July 17th, 2003
"Adenovirus (Ad)-specific T-cell responses in healthy adult donors were investigated. Ad5, inactivated by methylene blue plus visible light, induced proliferation and gamma interferon (IFN-gamma) production in peripheral blood mononuclear cells of the majority of donors. Responding T cells were CD4+ and produced IFN-gamma upon restimulation with infectious Ad5 and Ads of different subgroups," scientists writing in the Journal of Virology reported.
"T-cell clones showed distinct cross-reactivity patterns recognizing Ad serotypes from either one subgroup (C), two...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2003-07-17)
More Articles from Gene Therapy Weekly
- Oncology
Interferon-beta gene transfer protects against metastasis from uveal melanoma - Ophthalmology
Brain-derived neurotrophic factor preserves retinal function and cell survival - Drug Carriers
Encrypted polymers enhance intracellular delivery of oligonucleotides - Hematology
A high-expressing human factor IX plasmid corrects hemophilia B in mice - Myopathy
Pulsed electric fields accelerate gene transfer to differentiated muscle fibers - Vaccine Adjuvant
Intramuscular gene transfer gives a boost to antitumor DNA vaccine - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
