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Ophthalmology

Some viruses are promising vectors for intraocular gene delivery

Published in Gene Therapy Weekly, July 24th, 2003

Some viruses are promising vectors for intraocular gene delivery.

"There has been significant progress in the last few years in demonstrating the utility of recombinant viral vectors in treating a variety of ocular diseases. The field has moved beyond 'proof-of-principle' and, in fact, has entered the phase where some of these vectors/paradigms are being or soon will be evaluated in human clinical trials.

"For this reason and also, to increase the understanding of immunological effects of transgenes/viral vectors on the eye, it is important to summarize what is known about these effects," according to J. Bennett, University of Pennsylvania, Scheie...

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