Transfection
Dimerizer systems appear best for adenovirus-mediated gene induction
Published in Gene Therapy Weekly, July 31st, 2003
According to recent research from Japan, "positively and tightly regulated gene expression is essential for gene function and gene therapy research. The currently-used inducible gene expression systems include tetracycline (Tet-on and T-REx), ecdysone, antiprogestin and dimerizer-based systems. Adenovirus (Ad) vectors play an important role in gene function and gene therapy research for their various advantages over other vector systems."
"Previously, we reported the inferiority of the Tet-on system as an inducible gene expression system in the context of Ad vectors in comparison...
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Source: Gene Therapy Weekly (2003-07-31)
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