Chronic Hepatitis C
Antisense inhibition offers a new way to control hepatitis C virus infection
Published in Gene Therapy Weekly, August 14th, 2003
Researchers at Stanford University School of Medicine in California have used that strategy to knock out HCV controlled translation in mice, according to a report published in Hepatology.
"We assessed the inhibitory potential of morpholino phosphoramidate antisense oligonucleotides (morpholinos) on HCV translation by codelivering them with reporter plasmids expressing firefly luciferase under the translational control of the HCV internal ribosome entry site (IRES) into...
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Source: Gene Therapy Weekly (2003-08-14)
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