Amyotrophic Lateral Sclerosis

Gene therapy delays death in mouse with symptoms of ALS

Published in Gene Therapy Weekly, August 28th, 2003

It's not a cure, but a novel form of gene therapy has delayed symptoms and almost doubled life expectancy in mice with the equivalent of Lou Gehrig disease, a team from the Salk Institute and Johns Hopkins reports.

In experiments with mice destined to develop the condition, injection of the gene for insulin-like growth factor-1 (IGF-1) into muscles protected nerve cells, extended survival and improved strength, said the scientists, who are planning a clinical trial they hope to be able to begin in the next year.

The current study was published in the August 8, 2003, issue of Science.

The most beneficial treatment ever seen...

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Source: Gene Therapy Weekly (2003-08-28)

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