Breast Cancer
Estradiol enhances tumor regression in breast cancer models given gene therapy
Published in Gene Therapy Weekly, September 18th, 2003
"The majority of breast cancers are estrogen dependent and although current treatment strategies have improved, approximately 50% of the patients will develop metastasis. New treatments that result in long-term systemic immunity are therefore being developed. We have previously shown that adenoviral gene transfer of B7-1/IL-2 to murine breast cancer induces a high rate of complete tumor regression and systemic immunity," scientists in Sweden report.
"Since estrogens not only affect breast cancer but also have been shown to modulate immune function and secretion of...
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Source: Gene Therapy Weekly (2003-09-18)
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