Melanoma

Study raises prospect of practical vaccine

Published in Gene Therapy Weekly, September 25th, 2003

In a step toward a practical vaccine for advanced melanoma, a notoriously difficult-to-treat form of cancer, researchers at Dana-Farber Cancer Institute have demonstrated the effectiveness of a vaccine that is safer and easier to produce than earlier versions.

Writing in the September 1, 2003, issue of the Journal of Clinical Oncology, investigators led by Dana-Farber's Glenn Dranoff, MD, report that the vaccine, made by inserting a key gene into a patient's own melanoma cells, prompted a powerful immune system attack on melanoma tumors in several patients who received it in a clinical trial. More than 3 years after the trial began, 10 of the 35 patients who...

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Source: Gene Therapy Weekly (2003-09-25)

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