Gene Therapy
HIV-2 vectors suitable for treatment of Parkinson and Fabry disease
Published in Gene Therapy Weekly, October 23rd, 2003
"Lentiviral vectors are prime candidate vectors for gene transfer into dividing and non-dividing cells, including neuronal cells and stem cells," scientists in the United States explained. "For safety, HIV-2 lentiviral vectors may be better suited for gene transfer in humans than HIV-1 lentiviral vectors. HIV-2 vectors cross-packaged in HIV-1 cores may be even safer."
"Demonstration of the efficacy of these vectors in disease models will validate their usefulness," noted J. D'Costa and colleagues at the National Cancer Institute. "Parkinson's disease and Fabry...
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Source: Gene Therapy Weekly (2003-10-23)
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