Cardiology
Fusion between recipient- and donor-derived cells is a rare occurrence
Published in Gene Therapy Weekly, October 30th, 2003
"Despite recent advances in immunosuppressive therapy, accelerated coronary atherosclerosis remains a major problem in the long-term survival of cardiac transplant recipients. However, the pathogenesis of the transplant-associated atherosclerosis remains largely unknown. Here, we investigated the origin of the vascular cells that contribute to graft vasculopathy," scientists writing in the Journal of Surgical Research reported.
"We performed heterotopic heart transplantation using genetically modified mice that express LacZ or green fluorescent protein (GFP) ubiquitously...
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Source: Gene Therapy Weekly (2003-10-30)
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