Cancer Metastasis

Gene therapy containing p53 combines with CDDP to arrest liver tumor growth

Published in Gene Therapy Weekly, December 4th, 2003

Gene therapy containing p53 combines with CDDP to arrest liver tumor growth.

"Surgical resection is thought to be the best treatment for liver carcinoma, including hepatocellular carcinoma and metastatic liver carcinoma if there are a small number of tumors. Liver carcinoma is one of the main causes of death from cancer worldwide. The prognosis of liver carcinoma is still poor," researchers in Japan report.

"Mutation of p53, which is well known as a tumor suppressor gene, is observed in many cases of advanced liver carcinoma. Cancer gene therapy using p53, which transduces the wild-type p53 gene in the tumor, is a promising new strategy for treating...

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Source: Gene Therapy Weekly (2003-12-04)

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