Diagnostics
HPLC method validated for determination of ranitidine in plasma
Published in Gene Therapy Weekly, December 18th, 2003
"A validated HPLC method for the determination of ranitidine in human plasma is presented. Sulfanilamide as internal standard (IS) was used. Plasma samples were purified by solid phase extraction (SPE) using a copolymeric [poly(divinyl-benzene-co-N-vinylpyrrolidone)] column ('Oasis Waters')," researchers in Chile report.
"Mobile phase consisting of dibasic potassium phosphate 0.08 M/acetonitrile/methanol/triethylamine 0.05% (89.5:3:7:0.05) pH 5 was used at a flow rate of 0.9 mL/min on a C18 column (Nova-Pack, 3.9 x 300 mm, Waters)," wrote A. Castro and colleagues...
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Source: Gene Therapy Weekly (2003-12-18)
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