Brain Cancer
New MRI contrasts discern response to gene therapy in rodent glioma models
Published in Gene Therapy Weekly, January 15th, 2004
According to published research from Finland, "magnetic resonance imaging relaxation times, T-1rho and Carr-Purcell T-2 (CP-T-2), were measured in a glioma herpes simplex virus-thymidine kinase gene therapy model."
"In treated tumors with >50% cell death by histology, T-1rho and CP-T-2 measured with short spacing (tau(CP)) between centers of adiabatic refocusing pulses showed similar enhanced sensitivity to cytotoxic cell damage over CP-T2 measured with long tau(CP) (long-tau(CP) T-2: 54.3±0."7 and 55.4±1.2 ms, p=0.30; short-tau(CP) T-2: 61.3±1.0 and...
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Source: Gene Therapy Weekly (2004-01-15)
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