Gene Delivery
New ultradeformable cationic liposomes facilitate gene transfer
Published in Gene Therapy Weekly, January 29th, 2004
"Cationic lipids have been often used as one of the major components in making most promising nonviral gene delivery systems, whereas sodium cholate, a surfactant so-called edge activator has been used in preparing ultradeformable and ultraflexible liposomes called transfersomes. Using both a cationic lipid, DOTAP and sodium cholate, a novel formulation of ultradeformable cationic liposome (UCL) has been prepared. The average particle size of this formulation was approximately 80 nm," scientists in South Korea report.
"The physical and chemical stabilities at two different temperatures...
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Source: Gene Therapy Weekly (2004-01-29)
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