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Brain Injury

Immortalizing cells could aid brain and spinal cord repair

Published in Gene Therapy Weekly, March 4th, 2004

What if there were an unlimited supply of neural cells that could be transplanted into patients to treat diseases and injuries of the brain and spinal cord'

This futuristic scenario has become a shade more likely with the creation of "immortal" progenitor cells that give rise only to neurons. The new research, by Steven Goldman and colleagues, is described in the March 2004 issue of Nature Biotechnology.

The authors began by collecting human fetal neural progenitor cells. Such cells turn into neurons and glia during normal development, and may therefore be useful in transplantation therapies. A major problem with these cells, however, is that...

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