Gene Transfer
Mild electroporation is all that is required for muscle fiber transfection
Published in Gene Therapy Weekly, March 18th, 2004
"This study is a survey of in vivo experiments on transfection of laboratory mouse muscle fibers by electoporation using an original device generating electric impulses. Transfection efficiency proved to depend on DNA dose and the number of electric impulses. It can be increased significantly by electroporation at varying pulse burst polarity," scientists in Russia report.
"At both direct electrode application to muscles and electroporation through the skin, the muscle fiber transfection was more efficient under electroporation conditions much milder than those usually...
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Source: Gene Therapy Weekly (2004-03-18)
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