Gynecology

Cancer vaccine targets variant EGF receptor

Published in Gene Therapy Weekly, March 18th, 2004

Alteris Therapeutics, Inc., announced that it has licensed additional rights to its lead therapeutic vaccine, ALT-110, from Duke University and Johns Hopkins University. ALT-110 is a therapeutic vaccine targeting EGFRvIII, a tumor-specific splice variant of the epidermal growth factor receptor (EGFR).

Both universities have taken an equity stake in Alteris as part of the licensing agreement. ALT-110 was originally identified by Albert Wong, MD, a founder of Alteris, while he was a researcher at Johns Hopkins. Alteris has previously licensed other technology rights relevant to ALT-110 from Thomas Jefferson University.

Splice variants result when...

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Source: Gene Therapy Weekly (2004-03-18)

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