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Vector Development

Viral vectors prepared with TROMS extend transgene expression in mice

Published in Gene Therapy Weekly, March 18th, 2004

Viral vectors prepared with TROMS extend transgene expression in mice.

According to recent research published in the Journal of Controlled Release, "we have prepared and characterized injectable adenovirus-loaded polymeric microparticles to be used for in vitro and in vivo gene transfer studies. Microparticles were prepared by the water-in-oil-in-water solvent evaporation method using a novel system where the emulsification process is carried out by the turbulent injection of the phases in the total recirculation one-machine system (TROMS) apparatus."

"In vitro studies were performed to assess the amount of infectious adenovirus released from...

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