Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . April 8th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Immunology - CpG oligonucleotides elicit antitumor responses in melanoma models
Oncology - Double-ablated adenovirus has an affinity with tumor targets
Antimicrobial Therapy - Antioxidant gene therapy protects hearing against antibiotic-mediated injury
Hematology - Erythrocyte ghosts prolong plasmid DNA expression in the blood
Neuroscience - Bone marrow cells guide brain-derived neurotrophic factor genes into the brain
Ophthalmology - In utero gene delivery prevents congenital blindness in murine pups
Antisense Technology - A 2'-succinyl linker provides oligonucleotides new conduits for conjugation
Antisense Technology - Pluronic lends a hand to cationic liposomes bearing antisense oligonucleotides
Breast Cancer - Patent granted for mammary aspirate specimen cytology test
Collaborations - Genaera extends alliance IL-9 alliance
Collaborations - Isis Pharmaceuticals enters RNAi alliance
Collaborations - LSBC, partner to manufacture and distribute plant-produced recombinant aprotinin
Diarrhea - Trial results advance development of vaccine for travelers' diarrhea
Finance - Company reports net losses largely due to ATryn submission
Finance - Genomics-analysis company completes $4 million private equity financing
Gastroenterology - Angiopoietin-2 at deep rectal cancer invasion sites affirms a poor prognosis
Gene Deficiency - B cells develop and transcribe immunoglobulin despite Oct-1 deficiency
Gene Suppression - Bcl-2 small interfering RNA halts human tumor cell growth
Gene Transfer - Arginine-rich peptides stabilize polyplexed DNA to improve transduction
Gene Transfer - Avidin-displaying baculovirus enhances gene delivery
Gene Transfer - New avidin-biotin complexes may carry oligo-DNA to the liver
Genetic Engineering - Hapten-specific chimeras distinguish modified cell populations
Hepatitis B Vaccine - Bacteriophage-mediated nucleic acid immunization offers benefits
Hepatology - Cavernous hemangiomas are smaller in patients with chronic liver disease
Immunology - CpG methylation of plasmid vectors circumvents immune response activation
Immunology - Data presented on molecular mechanism of action for HE2000
Immunology - Expression by DNA-transfected DCs occurs through terminal differentiation
Immunology - Vectors harboring liver-restricted promoter yield long term gene expression
Influenza Vaccine - Influenza A viruses obtained from Vero cells by reverse genetics
Ischemia - Hepatocyte growth factor ameliorates perfusion without boosting tumor growth
Metastasis - Downregulated BRCA1 in melanoma modifies its metastatic potential
Neuroscience - Chimeric peptides look promising for delivering genes to select neurons
Neuroscience - Human glial fibrillary acidic promoter regulates transgenes in the brain
Public Opinion - Poll cites consumers' unfamiliarity with nonmedical biotech
Recombinant Research - Local gene therapy and immunosuppression promote osteoinductive activity
Rheumatology - Arthritis suppressor genes TIA-1 and TTP vanquish arthritogenic cytokines
Stem-Cell Research - BDNF gene-modified mesenchymal stem cells foster recovery after ischemic stroke
Vector Development - FV-based SIN vectors could potentially produce replication-competent revertants
Virology - DNA repair enzyme PK prevents adeno-associated virus DNA integration
cDNA Clones - GNF acquires TrueClone collection
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