Gynecology
THY1 correlates with tumor suppression in human ovarian cancer
Published in Gene Therapy Weekly, April 15th, 2004
"In our recent studies, the expression of the THY1 gene encoding a 25-28 kDa glycoprotein located at 11q23 approximately to q24, was found to be associated with complete tumor suppression of the ovarian cancer cell line SKOV-3 after the transfer of chromosome 11. These studies raised the possibility that THY1 maybe a candidate tumor suppressor gene for ovarian cancer. To investigate this, the complete cDNA sequence for THY1 was cloned and transfected into SKOV-3 ovarian cancer cells," investigators in the United States report.
"The expression of THY1 in the transfectants was confirmed by...
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Source: Gene Therapy Weekly (2004-04-15)
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