Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . April 22nd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Gastroenterology - Inducible nitric oxide synthase sensitizes colorectal cancer to radiation
Gynecology - The ceruloplasmin promoter shows an affinity for ovarian tumors
Biological Therapy - Silenced clusterin-apolipoprotein J gene causes cancer cells to implode
Gene Transfer - A new cleavage product gives real-time information about transgene activity
Immunology - Gene therapy in a murine multiple sclerosis model corrects disease
Pediatric Cancer - Herpes simplex virus thymidine kinase genes diminish nearby neuroblastoma cells
Assisted Reproduction - FDA approves Follistim AQ Cartridge
Asthma - Data supports benefits of second-generation immunomodulatory oligonucleotides
Biological Therapy - Altered Rho GTPase signaling pathways potential target for breast cancer therapy
Biotechnology - "Infectivity PCR" enhances detection of replication-competent adenovirus vectors
Breast Cancer - Androgen receptor polymorphism alters breast cancer risk in hormone therapy
Breast Cancer - Emmprin enhances several malignant properties of cancer cells
Breast Cancer - Prune cAMP phosphodiesterase binds nm23-H1 and promotes breast cancer metastasis
Breast Cancer - Rho GTPases represent signaling convergence points and relay switches
Cancer Therapy - Expanded roles for checkpoint kinases suggest target modification
Cardiology - Protein kinase C-alpha is a nodal integrator of cardiac contractility
Chemoresistance - Genomic alterations make cells more or less resistant to drug therapy
Colon Cancer - Beta-catenin may indirectly impact colorectal tumor progression or dormancy
Coronary Artery Disease - New growth factor protein helps damaged hearts
Diagnostic Imaging - Triple fusion reporter vectors identify gene expression in living subjects
Drug Delivery - Researchers creating polymers that act like biomolecules
Drug Resistance - Cancer-altered apoptosis leads to tumor progression and therapy resistance
Drug Resistance - MUC1 transforming protein confers resistance to genotoxic anticancer agents
Endocrinology - PPAR-delta regulates intestinal adenoma growth in mice
Enzymology - Matrix metalloproteinase-8 plays a key role in cancer metastasis
Finance - Cell-therapy company raises $10.7 million in series B financing
Gene Therapy Vectors - Sheep retrovirus Env efficiently pseudotypes HIV-based lentiviral vectors
Gene Transfer - Vectors encoding for angiostatin and endostatin surpass single-encoded vectors
Genetic Engineering - Genetically altered mice predict toxicity for individual targeted cancer therapy
Hematology - Cynomolgus macaques model the effects of hemophilia B gene therapy
Hepatology - COX-2-independent mechanisms steer the growth of cholangiocarcinoma
Metastasis - Powerful stem cells harnessed to search for cancer spread
Molecular Oncology - Cancer drug target Hsp90 susceptible to inhibition by 17AAG with cell activation
Nephrology - Gene therapy shows promise for treating renal diseases
Oncogenes - Mathematical approach used to understand cancer initiation and progression
Oncogenes - Mutations in more than 1% of cancer genes may contribute to human cancer
Oncogenes - Novel targeted expressed gene display analyzes alterations in genes
Oncogenesis - CBP loss mediates lymphomagenesis in synergy with reduction of p27(Kip1)
Patents - New nanobacteria patent announced
Personnel - Enzyme-focused company adds to management team
Proteomics - Syndecan-2 is required for angiogenic sprouting in developing embryos
Stem-Cell Research - Marrow stromal cells selected by serum deprivation express embryonic genes
Transplant Medicine - Cotransplanted third-party cells improve double cord blood transplantation
Tumor Suppression - SDHD is the first known tumor suppressor gene encoding a mitochondrial protein
Tumorigenesis - Aurora kinase inhibitor VX-680 suppresses tumor growth in vivo
Tumorigenesis - Specific PP2A complexes transform human cells to form or suppress tumors
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