Apoptosis
EGCG inhibits radiation-induced apoptosis by inactivating capase pathway
Published in Gene Therapy Weekly, May 6th, 2004
"Green tea is a rich source of polyphenols, and (-)-epigallocatechin-3-gallate (EGCG) is a major constituent of green tea polyphenols." The "effect of EGCG on apoptosis induced by irradiation" was investigated in the "keratinocytic cell line HaCaT. Irradiation by gamma-ray induced apoptosis with concomitant cleavage of caspase-3 and its in vivo substrate poly(ADP-ribose) polymerase," scientists in Japan wrote.
"Treatment of cells with EGCG inhibited irradiation-induced apoptosis as detected by Hoechst staining and internucleosomal cleavage of DNA,...
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Source: Gene Therapy Weekly (2004-05-06)
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