Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . May 13th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Drug Delivery - Adenoviral vectors rely on compatible materials for transfer effectiveness
Gene Induction - The introduction of VEGFR2 fragments into tumors slows their growth
Liver Cancer Therapy - Vesicular stomatitis virus infusions staunch hepatocellular carcinoma in rats
Transfection - CXCR4 restricts adenovirus-mediated transgene expression to tumor cells
Viral Vector - Ebola virus glycoproteins guide gene therapies to their destinations
Atherosclerosis - Apolipoprotein A-I gene transfer helps the arteries of apo E-deficient mice
Bacterial Genetics - In vivo expression technology identifies virulence genes in H. pylori
Brain Cancer - Cathepsin B inhibition suppresses angiogenesis in human glioblastoma cells
Breast Cancer - Estrogen receptor-alpha mutation K303R not found in Japanese breast carcinomas
Breast Cancer - Perillyl alcohol suppresses breast cancer cell growth in vitro and in vivo
Breast Cancer - Ring finger protein RNF11 important target for novel cancer therapies
Cancer Therapy - NCI grant to help company discover second-generation Hsp90 inhibitors
Cancer Therapy - Prodrugs becoming an integral part of the drug discovery paradigm
Cell Transduction - Intracellular MDA-7/IL-24 mediates activity in lung cancer cells
Colon Cancer - Biallelic MYH mutations confer susceptibility to colorectal cancer
Cystic Fibrosis - Scientists create mouse model answering central question - lungs lack water
Drug Discovery - Challenges of virtual screening for kinase targets demystified
Endocrinology - Menin inactivation leads to parathyroid tumorigenesis
Expansion - Insmed acquires manufacturing facility; will be used for SomatoKine
Finance - Renagel maker reports financial results for first quarter
Gastrointestinal Tumors - Telomerase inhibitor PinX1 not involved in gastrointestinal tract carcinoma
Gene Transfer - Alginate puts a damper on viral leakage after gene delivery
Genomics - Collaboration with p53 and p63, p73 responds to cell genotoxic damage
Genomics - LCR promotes beta-globin transcription repression in committed cells
Hepatology - Mechanical massage enhances liver cell gene transfer in the mouse
Immunology - Interleukin-10-related cytokines and their receptors are therapeutic targets
Molecular Virology - Promoter activity of AVL-A LTR region related to induction of glial neoplasm
Mutagenesis - FGFR3 and P53 mutations affect pathogenesis of urothelial cell carcinoma
Mutations - CHEK2*1100delC mutation has no major contribution in esophageal carcinogenesis
Neisseria - PilE protein antigens of Neisseria selected by recombination
Neuroscience - Virus-mediated gene transfer reverses rubrospinal neuron atrophy
Personnel - Stem cell pioneer Dr. Nelson Chao named to advisory board
Prion Disease - Hyperbaric oxygen enhances expression of prion and heat shock proteins
Prostate Cancer - Novel cooperation up-regulate vitamin D receptor protein
Pulmonary Medicine - Viscous solutions propel adeno-associated virus vectors to the diaphragm
Transformation - Autocrine stimulation by osteopontin sustains carcinoma proliferation in vitro
Transgenics - Viral capsids will make new gene therapies feasible
Tumor Suppression - Acetylation of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
Tumorigenesis - Fbw7 essential in controlling cyclin E and Notch signaling pathways
Vaccine Delivery - DNA virus-like particles elicit immune responses by oral administration
Vector Development - The adenovirus E4 gene encourages endothelial cell survival and angiogenesis
Virology - New recombinant viral vectors have enhanced gene transfer capabilities
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