Published in Gene Therapy Weekly, May 20th, 2004
"Chromosome 13 is the largest acrocentric human chromosome. It carries genes involved in cancer including the breast cancer type 2 (BRCA2) and retinoblastoma (RB1) genes, is frequently rearranged in B-cell chronic lymphocytic leukaemia, and contains the DAOA locus associated with bipolar disorder and schizophrenia. We describe completion and analysis of 95.5 megabases (Mb) of sequence from chromosome 13, which contains 633 genes and 296 pseudogenes," wrote scientists in England.
Estimates are that "more than 95.4% of the protein-coding genes of this chromosome have been identified, on the basis...
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