Published in Gene Therapy Weekly, May 27th, 2004
"During the past decade, the search for an effective system for the selective delivery of high therapeutic doses of anticancer agents to tumors has explored a variety of ingenious and increasingly complex biological systems. These systems are most often based on gene therapy and use viral vectors as the delivery vehicle," say scientists in England.
"Invariably, such systems have been found wanting with respect to a lack of tumor specificity, poor levels of transgene expression and inefficient distribution of the vector throughout the tumor mass," according to N.P. Minton and...
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