Epilepsy
Neuropeptide Y transfection diminishes epileptic activity in rats
Published in Gene Therapy Weekly, May 27th, 2004
"Neuropeptide Y (NPY) inhibits seizures in experimental models and reduces excitability in human epileptic tissue. We studied the effect of long-lasting NPY overexpression in the rat hippocampus with local application of recombinant adeno-associated viral (AAV) vectors on acute kainate seizures and kindling epileptogenesis," scientists in Italy report.
"Transgene expression was significantly increased by 7 days, reached maximal expression by 2 weeks, and persisted for at least 3 months," stated C. Richichi and colleagues, Mario Negri Institute of Pharmacology Research, Department of...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2004-05-27)
More Articles from Gene Therapy Weekly
- Cancer Therapy
Clostridia spores offer a natural alternative for tumor targeting - Pulmonary Medicine
HSV type 1 thymidine kinase/ganciclovir gene therapy targets lung cancer - Transfection
Single-step surfection eases gene transfer and drug screening - Virology
Adenovirus vector libraries provide clues about gene and protein function - Alcoholism
Gene therapy reduces drinking in rats with predisposition to alcohol abuse - Angiology
Autologous vascular smooth muscle cells are a conduit for cardiac gene transfer - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
