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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . June 3rd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Adenoviral Vector - The survivin promoter is tumor-specific in virus-mediated gene therapy

Cancer Therapy - Antisense inhibitor of methylated DNA-binding protein 2 blocks new tumors

Head and Neck Cancer - A new system shows adenoviruses elicit poor transduction in esophageal cancer

Radiotherapy - PTEN transfection sensitizes prostate cancer cells to radiation therapy

Vector Development - Carrier cells mediate the transfer of oncolytic parvovirus to metastatic tumors

Alzheimer Disease - APP contributes to inflammatory condition in Alzheimer disease

Alzheimer Disease - Plans to further develop Alzheimer disease gene therapy confirmed

Antimicrobials - Animal microbes pass glycopeptide resistance genes to humans

Bioengineering - A new recombinant polymer augments angiogenesis and other functions

Brain Tumor - Radiation-induced activation of caspase-9 blocks glioma invasion

Cancer Therapy - Company seeks partner for Immunogene therapy for cancer

Cardiac Repair - A heme oxygenase-1 plasmid system protects the heart from ischemic injury

Cell Biology - The anti-proliferation gene BTG1 mediates angiogenic activity

Cell Therapy - TALL-104 cells injure glioma cells by apoptotic and necrotic pathways

Cell biology - Thiol depletion aids bax-induced programmed cell death in lung cancer cells

Cloning - Company provides two NIH agencies with open access to cloning technologies

Collaborations - Isis announces extension of antisense cancer drug-discovery collaboration

Diagnostics - Recombinant ELISA highly sensitive and specific for clonorchiasis diagnosis

Drug Delivery - Hydrodynamic injection accomplishes transduction through hydroporation

Drug Discovery - TrueClone Kinase Collection acquired for high-throughput drug target discovery

Finance - Affinitak maker reports decrease in revenues during first quarter

Gene Transfer - In vivo gene delivery with regulatable lentivirus surveys neurogenic function

Genomics -  T. brucei genes encode functional PMCAs essential for Ca2+ homeostasis

HIV/AIDS - V82F/184V mutation decreases binding affinity of HIV-1 protease inhibitors

Immunology - Coexpressed CCL21/SLC and LIGHT diminish tumor growth and increase survival

Immunology - Estrogen receptor beta localized to mitochondria

Immunology - Immunomodulatory oligonucleotides containing CpR motifs attack tumors

Myocardial Infarction - Skeletal myoblasts that secrete interleukin-1 inhibitor control remodeling

Oligonucleotide - 2'-O,4'-C-ethylene-bridged nucleic acids help oligonucleotides resist enzymes

Prostate Cancer - Id-1 signals support androgen-independent prostate cancer cell growth

Prostate Cancer - Muscle-derived cells and gene therapy may cure for post-prostatectomy ED

Proteomics - Tumor necrosis factor and monocyte chemoattractant protein aid myeloma travel

Stem-Cell Research - Direct Dlx homeodomain target identified in developing forebrain and retina

Stem-Cell Research - Embryonic stem cell gene array expression profiling leads to functional analysis

Tumor Suppressor Gene - Large intestinal tumors induced by o-Nitrotoluene in B6C3F1 mouse model

Urology - Vectors bearing the uroplakin II promoter staunch bladder cancer

Vector Development - Ovine atadenovirus finding application as gene delivery vector

Viral Oncolysis - The DF3/MUC1 promoter gives oncolytic virus a boost

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