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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . June 10th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Bioengineering - Genetically modified Sertoli cells survive allogeneic transplantation

Cancer Therapy - Combined therapy rallies caspase activation to staunch glioma growth

Genetic Engineering - Cytokine gene therapy reverts melanoma growth in mice

Oncolysis - The oncolytic adenovirus CG7870 attacks recurrent prostate cancers

Wound Care - Exogenous insulin-like growth factor gene transfer enriches wound healing

Acute Coronary Syndromes - Company announces reinitiation of phase IIa trial in ACS

Bioengineering - Artificial cells will pave the way for new treatment modalities

Biomaterial - Modifications shield encapsulated cells from unwelcome calcification

Cancer Research - Hedgehog pathway implicated in ameloblastoma

Cancer Therapy - Company initiates clinical trial of GCS-100LE in multiple cancers

Cancer Therapy - IMOxine produces immunological activity in those with solid-tumor malignancies

Cancer Treatment - Research indicates virus may destroy cancerous cells in lung

Cardiology - Signals from p38 influence the mortality of cardiac cells

DNA Vaccine - Plasmid DNA integrates into host genomic DNA after injection

Diagnostics - Ets gene family may be involved in biological control of cancer progression

Endocrinology - Nutritional dynamics influence hypothalamic gene expression

Finance - BeadArray developer to raise $30 million in registered offering

Finance - DNA-focused company reports 74% revenue increase

Gene Expression - Novel binding elements and gene targets for homeodomain protein BARX2 identified

Gene Expression - Study may predict recurrence of head and neck cancer

Gene Suppression - The p53 gene regulates estrogen receptor-alpha in breast cancer cells

Gene Transfer - Transcription-control mediated gene therapy blocks tumor angiogenesis

Genetics - New gene discovery may lead to prenatal test for disease

Genome Technology - Institute grants $2.4 million grant for genome sequencing technology development

Genomics -  Cryptosporidium parvum genome completely sequenced

Human Cloning - Louisiana Senate allows cloned cells for research but bans reproductive cloning

Immunology - Antigen Express wins Japanese patent for certain Ii-Key compounds

Immunology - Interferon-beta gene delivery blocks the formation of autoimmune myocarditis

Oncogenesis - Researchers discuss insights into p53 and cell death

Osteogenesis - Human LIM mineralization protein-3 stimulates new bone formation

Otolaryngology - Adenovirus-mediated gene transfer causes minimal harm to auditory hair cells

Patents - Company receives broad patent for purified adenoviral compositions

Pediatric Cancer - Bovine herpesvirus VP22 enhances neuroblastoma self-destruction

Product Licensing - Geron enters telomerase licensing agreement

Prostate Cancer - Study: MetaMouse model predicts recurrence in human prostate cancer patients

Protein Synthesis - Recombinant endostatin can be synthesized in Chinese hamster ovary cells

Pulmonary Medicine - Anti-monocyte chemoattractant protein-1 gene therapy limits pulmonary fibrosis

Restenosis - Nogo-B gene transfer rescues vessels from abnormal remodeling

Stem Cells - Britain opens world's first national stem cell bank

Vector Development - Cationic pharmacophores provide potent nonviral gene delivery

Vector Development - RNA interference via transposon-based delivery offers long-term knockdown

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