Cancer Therapy
Combined therapy rallies caspase activation to staunch glioma growth
Published in Gene Therapy Weekly, June 10th, 2004
According to a study from the United States, "specific activation of apoptosis in tumor cells offers a promising approach for cancer therapy. Induction of apoptosis leads to activation of specific proteases. Two major pathways for caspase activation in mammalian cells have been described."
"One apoptotic pathway involves members of the tumor necrosis factor family of cytokine receptors (e.g. death receptor 5 (DR5)). The other pathway is controlled by the Bcl-2 family of proteins. The purpose of this study was to investigate whether increased apoptosis occurs in human glioma cells...
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Source: Gene Therapy Weekly (2004-06-10)
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