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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . June 17th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Acute Lymphoid Leukemia - Combinatorial gene therapy offers antitumor protection to leukemia models

Bioengineering - A novel genetically engineered marker keeps track of stem cells in vivo

Restenosis - Implanted stents with c-myc suppressant engender arterial healing

Transplant Medicine - Hepatocyte growth factor expands outcomes after islet transplantation

Vector Development - Herpesvirus-based vector systems provide for efficient transduction

AIDS Therapy - Researchers explore gene treatment to obliterate HIV before it does damage

Amyotrophic Lateral Sclerosis - Gene therapy with growth factor seems promising for incurable muscle disorder

Appetite - Researchers target genes with viruses to select populations of nerve cells

Autoimmune Disease - IL-6 provokes a gene linked to systemic lupus erythematosus susceptibility

Biotechnology - FRET-based analysis detects subtle change in early cycle-related gene activation

Brain Cancer - Cationic lipid-DNA complexes slow glioblastoma growth in murine models

Brain Cancer - Technology blocks gene to increase immune response against brain tumor cells

Cervical Cancer - Recombinant adenovirus p53 effects cancer cell apoptosis

Cirrhosis - Gene induction eliminates fibrogenic stellate cells in the liver

Cloning - Researchers clone calf from cloned bull

DNA Vaccine - Apoptosis increases efficacy of alphaviral replicase-based DNA vaccines

DNA Vaccine - DNA vaccine may protect piglets against porcine circovirus type 2

Diabetes Therapy - Vascular endothelial growth factor supports islet graft survival

Diabetic Nephropathy - Hepatocyte growth factor gene transfer may treat diabetic kidney disease

Drug Development - Antisense oligonucleotide LErafAON enhances the work of standard chemotherapy

Drug Development - Chimeric receptors fuel cytotoxicity against acute lymphoblastic leukemia

Drug Development - ReceptoPharm completes first step in production of RPI-78M.

Epstein-Barr Virus - EBV-induced growth proliferation inhibited by nuclear antigen EBNA2-TAT peptide

Gene Correction - Adeno-associated virus vectors correct single base pair mutations

Gene Delivery - Multi-particle tracking characterizes real-time gene trafficking

Gene Mutation - Mutations in gene encoding filamin B disrupt vertebral segmentation

Gene Transfer - Heme oxygenase-1 gene transfer induces long-term cardiac allograft survival

Genetic Marker - Nup88 mRNA overexpression associated with high aggressiveness of breast cancer

Genetics & Genomics - GNB3 gene associated with pulse pressure and risk for cardiovascular disease

Genomics - CRE-II site in SMN promoter positively regulates expression of SMN gene

Genomics - Dog genome may hold a wealth of information for humans

Genomics - Structural character of siRNA important determinant of siRNA efficiency

Genomics - mtDNA 10398 polymorphism related to maintenance lithium treatment response

Genomics - p65 peptide identified that selectively inhibits NF-kappa B activation

Hematology - Forced Notch4 expression holds myeloid cell differentiation at bay

Hematology - Lung cells give rise to lymphohematopoietic cells in irradiated animals

Hematology - Vascularizing tumors actively recruit bone marrow stromal progenitor cells

Hepatitis - Publication highlights antiviral activity of NEUGENE antisense compound

Immunology - T cells and macrophages main BAFF-expressing cells in salivary glands from pSS

Leukemia - Study looks at marrow stem cells and chemotherapy

Liver Regeneration - Hepatocyte growth factor required for efficient liver regeneration and repair

Prognostics - p53 over-expression correlates with local treatment failure in oral carcinoma

Pulmonary Medicine - Hepatoma-derived growth factor encourages lung remodeling after injury

Stem Cell Research - Self-renewal capacity is a widespread property of neural crest precursor cells

Thyroid Tumors - Cyclin D1 overexpression is significant in thyroid tumors

Transfection - Expression system secretes TAT fusion proteins

Vasculopathy - Epidermal progenitor cells help restore blood flow in diabetic ischemic limbs

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