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Dermatitis

Allergens from M. sympodialis may play role in atopic eczema/dermatitis syndrome

Published in Gene Therapy Weekly, July 8th, 2004

Allergens from the yeast Malassezia sympodialis may play a role in atopic eczema/dermatitis syndrome.

According to recent research from Sweden, "Malassezia sympodialis is an opportunistic yeast that colonizes human skin and may induce IgE and T cell reactivity in patients with atopic eczema/dermatitis syndrome (AEDS). Previously, we have cloned and expressed six recombinant allergens (rMala s 1 and rMala s 5 to rMala s 9) from this yeast."

"By combining high throughput screening and phage surface display techniques," wrote A. Andersson and coworkers, "27 complete and partial IgE-binding clones of M. sympodialis have been...

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